Formulation and in Vitro Evaluation of Mouth Dissolving Tablet of Olanzapine Using Solid Dispersion Technique
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چکیده
منابع مشابه
Development and in vitro evaluation of ibuprofen mouth dissolving tablets using solid dispersion technique.
The aim of present study was to prepare and evaluate mouth dissolving tablets of ibuprofen (IBU). Ternary solid dispersion (SD) of IBU was prepared using PEG 4000 as carrier and Tween 80 as surfactant. The SD formulations were prepared by solvent evaporation and melt solvent method by varying ratio of PEG 4000. Different weight ratio of carrier, drug and surfactant 5 : 5 : 1, 10 : 5 : 1, 25 : 5...
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Conventional solid dosage form suffers from problem like difficulty in swallowing with age, onset of action and physiological factor of patient like gastric emptying time. To overcome this mouth dissolving tablet is a newer approach to drug delivery. Zolpidem is preferentially used for the short term treatment of insomnia. The aim of present study is to formulate and evaluate mouth dissolving t...
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Mouth dissolving tablets are solid dosage forms containing drugs that disintegrate in the oral cavity within less than one minute leaving an easy-to-swallow residue. In the recent trend the development of mouth dissolving tablets formulation is emerging and gaining popularity because it is easy to administer and leads to better patient compliance. These dosage forms are placed in the mouth, all...
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s: Mouth dissolving tablet is the fast growing and highly accepted drug delivery system. This study was aimed at development of Ketorolac Tromethamine mouth dissolving tablet, which can disintegrate or dissolve rapidly once placed in the oral cavity. Conventional Ketorolac tromethamine tablet require water to swallow it and have disadvantages like low disintegration rate, low solubility etc.Ket...
متن کاملFormulation Development and Evaluation of Mouth Dissolving Tablet of Tramadol Hydrochloride
Many patient groups, such as the elderly, children, mentally retarded, uncooperative or nauseated, have difficulty in swallowing conventional dosage forms, like tablets. Swallowing conventional tablets will be further hindered by conditions such as unavailability of water, allergic reactions and episodes of coughing1. These problems can be solved by developing rapidly disintegrating and dissolv...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Research
سال: 2012
ISSN: 2454-8405,0973-7200
DOI: 10.18579/jpcrkc/2012/11/4/79364